November 16, 2023

1 min read


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Experts have the ability to genetically screen embryos for a variety of diseases, but questions remain about which diseases should be screened, according to Sigal Klipstein, MD.

“Should you test only for life-limiting diseases that lead to death in childhood?” she asked “Should you test for diseases that can decrease life expectancy? Should you test for diseases that don’t develop until later in life? And what about predispositions for diseases like breast cancer?”





Experts have the ability to genetically screen embryos for a variety of diseases, but questions remain about which diseases should be screened, according to Sigal Klipstein, MD.

Healio spoke with Klipstein about these ethical questions and what the future of reproductive endocrinology and infertility might hold. It was the top story in women’s health last week.

The second top story was about a study that showed premenopausal women who received one-daily Orilissa (elagolix, AbbVie) experienced a reduction in heavy menstrual bleeding.

Read these and more top stories in women’s health below:

Ethical dilemmas in genetic embryo testing: A discussion with Sigal Klipstein, MD

As a child, Klipstein would visit the Museum of Science and Industry in Chicago with her parents and be intrigued by the developing human exhibit, where she saw the progression of embryos to fetuses. Read more.

Once-daily elagolix significantly reduces heavy menstrual bleeding for premenopausal women

Elagolix 150 mg once daily significantly reduced heavy menstrual bleeding from uterine leiomyomas among premenopausal women, according to trial results published in Obstetrics & Gynecology. Read more.

Exposure to nitrogen dioxide, particulate matter increases miscarriage risk

Exposure to air pollution around the time of conception was linked to an increased risk for miscarriage compared with less exposure, according to study results presented at the ASRM Scientific Congress & Expo. Read more.

Early induced abortion not a risk factor for Rh sensitization

Induced abortion during the first trimester did not increase risk for Rh sensitization, which suggests that Rh testing and treatment in pregnancy is unnecessary before 12 weeks gestation, researchers reported in JAMA. Read more.

First-trimester cesarean scar pregnancy manageable with some surgical, medical treatments

Cesarean scar pregnancy in the first trimester can be effectively managed through suction evacuation, balloon treatment or surgical excision, researchers reported in the American Journal of Obstetrics and Gynecology. Read more.